Protein Alignment tpr and Klk12

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_081373.1
• Gene: Klk12 / 69511
• MGIID: 1916761
• Length: 247
• Species: Mus musculus
• Alignment Length: 255
• Identity: 86/255 - (33%)
• Similarity: 133/255 - (52%)
• Gaps: 38/255 - (14%)

  Fly   116 CVCGIANI-QKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISV 179
            |..|::.. :::|..|.|...:..||...|.:|....|...|::.:::|||:||     :::..|
Mouse    10 CAVGLSQADREKIYNGVECVKNSQPWQVGLFHGKYLRCGGVLVDRKWVLTAAHC-----RDKYVV 69

  Fly   180 RLLEHDRKMSHMQKID-----RKVAEVITHPKYNA--RNYDNDIAIIKLDEPVEFNEVLHPVCMP 237
            ||.||.     :.|:|     |.....||||.|..  :|:::|:.:::|:.|:.....:.||.:|
Mouse    70 RLGEHS-----LTKLDWTEQLRHTTFSITHPSYQGAYQNHEHDLRLLRLNRPIHLTRAVRPVALP 129

  Fly   238 ----TPGRSFKGENGIVTGWGAL-KVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGY 297
                |.|....     |:|||.. |...|..|.||.:.:..:|.:.|| :.:..::|:||||.|
Mouse   130 SSCVTTGAMCH-----VSGWGTTNKPWDPFPDRLQCLNLSTVSNETCR-AVFPGRVTENMLCAG- 187

  Fly   298 DEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGE--GCAKAGYPGVYARVNRYGTWIK 355
            .|.|||:|||||||||  |..|.    :.|:||||.  .|.:.|.||||.:|.:|..||:
Mouse   188 GEAGKDACQGDSGGPL--VCGGV----LQGLVSWGSVGPCGQKGIPGVYTKVCKYTDWIR 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	84/243 (35%)
Klk12	NP_081373.1	Tryp_SPc	21..240	CDD:214473	82/241 (34%)