Protein Alignment tpr and Klk5

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_081082.1
• Gene: Klk5 / 68668
• MGIID: 1915918
• Length: 293
• Species: Mus musculus
• Alignment Length: 296
• Identity: 92/296 - (31%)
• Similarity: 146/296 - (49%)
• Gaps: 53/296 - (17%)

  Fly    78 AASTTSTTTPAPSSSTTTTRRATTPAPPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVA 142
            |...:|...|:.:..:.|.|..:|.:....:...:.|          .|||.|.:.:....||..
Mouse    29 AGDVSSCDNPSGTEPSGTNRDLSTDSKSGEDTRSDSS----------SRIVNGSDCQKDAQPWQG 83

  Fly   143 MLLYG-GRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMSHMQKIDRKV---AEVIT 203
            .||.| .:.||.|.|::.|:||||:||    ||....:||..|  .||.:.:..:::   .:.|.
Mouse    84 ALLLGPNKLYCGAVLISPQWLLTAAHC----RKPVFRIRLGHH--SMSPVYESGQQMFQGIKSIP 142

  Fly   204 HPKYNARNYDNDIAIIKLDEPVEFNEVLHPV-----CMPTPGRSFKGENGIVTGWGALKVGGPTS 263
            ||.|:...:.||:.:||::..:..:..:.||     |      :.:|...:|:|||.      ||
Mouse   143 HPGYSHPGHSNDLMLIKMNRKIRDSHSVKPVEIACDC------ATEGTRCMVSGWGT------TS 195

  Fly   264 DT-------LQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTR 321
            .:       ||.:.:.:||::.|:.| |..:|...|.|.| ||.|:||||||||||  :|.:|
Mouse   196 SSHNNFPKVLQCLNITVLSEERCKNS-YPGQIDKTMFCAG-DEEGRDSCQGDSGGP--VVCNG-- 254

  Fly   322 EHQIAGVVSWGE-GCAKAGYPGVYARVNRYGTWIKN 356
              ::.|:||||: .||:...||||..:..:..|||:
Mouse   255 --KLQGLVSWGDFPCAQRNRPGVYTNLCEFVKWIKD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	83/245 (34%)
Klk5	NP_081082.1	Tryp_SPc	67..286	CDD:214473	82/244 (34%)