Protein Alignment tpr and PRSS56

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 115/333 - (34%)
• Similarity: 160/333 - (48%)
• Gaps: 29/333 - (8%)

  Fly    48 VLSLLPQRPGSSDSENATLAT-LSSSSMMPDAASTTSTTTPAPSSSTTTTRRAT----------- 100
            ||.||| .|.|..:....|.| |..|::...:|..|.....|..|:.....|..
Human     5 VLLLLP-LPSSWFAHGHPLYTRLPPSALQVLSAQGTQALQAAQRSAQWAINRVAMEIQHRSHECR 68

  Fly   101 ---TPAPPTL--NPPR--NCSDCVCGIANIQK---RIVGGQETEVHQYPWVAMLLYGGRFYCAAS 155
               .|.|..|  :||.  .|.:.....||:.:   |||||.......:||:..|..||:..|...
Human    69 GSGRPRPQALLQDPPEPGPCGERRPSTANVTRAHGRIVGGSAAPPGAWPWLVRLQLGGQPLCGGV 133

  Fly   156 LLNDQFLLTASHCVYGFRKERI-SVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAII 219
            |:...::|||:||..|...|.: :|.|.|..|   ..|..:..|..::.|||::.|.:.||:|::
Human   134 LVAASWVLTAAHCFVGAPNELLWTVTLAEGSR---GEQAEEVPVNRILPHPKFDPRTFHNDLALV 195

  Fly   220 KLDEPVEFNEVLHPVCMP-TPGRSFKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSR 283
            :|..||.......|||:| .|.....|....:.|||||...||.::.::|.:||:||.|.||::.
Human   196 QLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRAL 260

  Fly   284 YGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIA-GVVSWGEGCAKAGYPGVYARV 347
            ........|||.||..||.|||||||||||.....|.|..::. ||.|||:||.:.|.||||.||
Human   261 GPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRV 325

  Fly   348 NRYGTWIK 355
            ..:..|::
Human   326 AVFKDWLQ 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	90/232 (39%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	90/232 (39%)
		PksD	<178..600	CDD:442550	66/156 (42%)