Protein Alignment tpr and TPSB2

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 95/274 - (34%)
• Similarity: 142/274 - (51%)
• Gaps: 35/274 - (12%)

  Fly    96 TRRATTPAPPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRF---YCAASLL 157
            :|....|||              |.|..:..||||||....::||...|....|:   :|..||:
Human    14 SRAYAAPAP--------------GQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLI 64

  Fly   158 NDQFLLTASHCVYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLD 222
            :.|::|||:|||....|:..::|:...::.:.:..:: ..|:.:|.||::.......|||:::|:
Human    65 HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQL-LPVSRIIVHPQFYTAQIGADIALLELE 128

  Fly   223 EPVEFNEVLHPVCMPTPGRSF-KGENGIVTGWGALKVGG--PTSDTLQEVQVPILSQDECRKSRY 284
            |||..:..:|.|.:|....:| .|....|||||.:....  |....|::|:|||:....| .::|
Human   129 EPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC-DAKY 192

  Fly   285 ------GNK---ITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGY 340
                  |:.   :.|:|||.|...  :|||||||||||....:||...  |||||||||||:...
Human   193 HLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQ--AGVVSWGEGCAQPNR 253

  Fly   341 PGVYARVNRYGTWI 354
            ||:|.||..|..||
Human   254 PGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	89/243 (37%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	89/243 (37%)