Protein Alignment tpr and hpn

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001091657.2
• Gene: hpn / 569259
• ZFINID: ZDB-GENE-141212-373
• Length: 425
• Species: Danio rerio
• Alignment Length: 374
• Identity: 118/374 - (31%)
• Similarity: 173/374 - (46%)
• Gaps: 62/374 - (16%)

  Fly    26 RATNQT--------AASPLLKQSQNTFIQWVLSLLPQRPGSSDSENATLATLSSSSM-MPDAAST 81
            |.|..|        ||...|:...:|..:|       :...|.|.|..:|.::...| ...|.:.
Zfish    47 RTTEDTGLFDVQVSAADQRLRVFDSTQWRW-------KYVCSSSVNQLIANITCEEMGFVRAVNF 104

  Fly    82 TSTTTP----------APSSSTTTTRRATTPAPPTLNPPRNCSDCVCGIANI------------- 123
            :.|..|          ...|..|..::..|...|          |.|....|
Zfish   105 SVTCAPESGGDRDFFCVKESELTYGKKIKTALYP----------CKCDKGQILEVICQDCGRRML 159

  Fly   124 -QKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRK 187
             ::|||||.:.....:||...|.|.|...|..|:::|:::::|:||.....:.....|:|.....
Zfish   160 PEERIVGGVDARQGSWPWQVSLQYDGVHQCGGSIISDRWIISAAHCFPERYRHASRWRVLMGSIY 224

  Fly   188 MSHMQK--IDRKVAEVITHPKY------NARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPG-RSF 243
            .:.::|  :..:|..|:.|..|      |..:...|||:|.|.:|::|.:.:.|||:||.| |..
Zfish   225 NTPIRKNVVIAEVKTVVYHSSYLPFVDANIDDNSRDIAVISLTKPLQFTDYIQPVCLPTYGQRLA 289

  Fly   244 KGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECR-KSRYGNKITDNMLCGGYDEGGKDSCQG 307
            .|:.|.|||||.::..|..::.|||..|||:|...|. ...|.|::|..|.|.||::||.|||||
Zfish   290 DGQMGTVTGWGNVEYYGTQANVLQEAHVPIISDAVCNGPDYYDNQVTTTMFCAGYEKGGTDSCQG 354

  Fly   308 DSGGPLHI--VASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI 354
            |||||...  |.|.|..:::.||||||.|||.|..||||.||:|:..||
Zfish   355 DSGGPFVAADVLSKTSRYRLLGVVSWGTGCAMAKKPGVYTRVSRFLPWI 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	94/240 (39%)
hpn	NP_001091657.2	Hepsin-SRCR	53..160	CDD:462736	20/123 (16%)
		Tryp_SPc	164..404	CDD:238113	94/240 (39%)