Protein Alignment tpr and KLK6

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 84/247 - (34%)
• Similarity: 128/247 - (51%)
• Gaps: 25/247 - (10%)

  Fly   121 ANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHD 185
            |..|.::|.|...:...:|:.|.|...|...|...|::..::|||:||    :|..:.|.|.:|:
Human    16 AEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLGKHN 76

  Fly   186 RKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPV-----CMPTPGRSFKG 245
            .:.....:....|...:.||.|:|.::|.||.:::|..|.:.:|::.|:     |      |...
Human    77 LRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDC------SANT 135

  Fly   246 ENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSG 310
            .:..:.|||. ...|...||:|...:.::|::||..: |..:||.||||.|.::.||||||||||
Human   136 TSCHILGWGK-TADGDFPDTIQCAYIHLVSREECEHA-YPGQITQNMLCAGDEKYGKDSCQGDSG 198

  Fly   311 GPLHIVASGTREHQIAGVVSWGE-GCAKAGYPGVYARVNRYGTWIKNLTKQA 361
            |||   ..|  :| :.|:||||. .|.....||||..|.||..||:. |.||
Human   199 GPL---VCG--DH-LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQK-TIQA 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	79/234 (34%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	77/231 (33%)