Protein Alignment tpr and KLK7

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 75/242 - (30%)
• Similarity: 123/242 - (50%)
• Gaps: 26/242 - (10%)

  Fly   126 RIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMSH 190
            :|:.|.......:||...||.|.:.:|...|:|::::|||:||    :....:|.|.........
Human    29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTLGDRR 89

  Fly   191 MQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPT----PGRSFKGENGIVT 251
            .|:|  |.::...||.|:.:.:.||:.::||:.....:.::..|.:|:    ||.:.     .|:
Human    90 AQRI--KASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC-----TVS 147

  Fly   252 GWGALKVGGPT--SDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLH 314
            |||.......|  || |..|.|.::|..:|.|. |.:.:.::|||.|..:..|::|.|||||||
Human   148 GWGTTTSPDVTFPSD-LMCVDVKLISPQDCTKV-YKDLLENSMLCAGIPDSKKNACNGDSGGPL- 209

  Fly   315 IVASGTREHQIAGVVSWGE-GCAKAGYPGVYARVNRYGTWIKNLTKQ 360
             |..||    :.|:||||. .|.:...||||.:|.::..||.:..|:
Human   210 -VCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	74/235 (31%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	72/234 (31%)