Protein Alignment tpr and PRSS3

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001184026.3
• Gene: PRSS3 / 5646
• HGNCID: 9486
• Length: 261
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 103/256 - (40%)
• Similarity: 144/256 - (56%)
• Gaps: 19/256 - (7%)

  Fly   103 APPTLNPPRNCSDCVCGIA-NIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTAS 166
            ||...:||    |.:..:. :...:||||...|.:..|:...|..|..| |..||:::|::::|:
Human    17 APLVFHPP----DALIAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAA 76

  Fly   167 HCVYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVL 231
            ||.    |.||.|||.||:.|:....:.....|::|.|||||....||||.:|||..|...|..:
Human    77 HCY----KTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 137

  Fly   232 HPVCMPTPGRSFKGENGIVTGWG-ALKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCG 295
            ..:.:||...: .|...:::||| .|..|....|.|:.:..|:|:|.|| |:.|..|||::|.|.
Human   138 STISLPTTPPA-AGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAEC-KASYPGKITNSMFCV 200

  Fly   296 GYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKN 356
            |:.||||||||.|||||  :|.:|    |:.||||||.|||....||||.:|..|..|||:
Human   201 GFLEGGKDSCQRDSGGP--VVCNG----QLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	97/229 (42%)
PRSS3	NP_001184026.3	Tryp_SPc	38..256	CDD:238113	98/231 (42%)