Protein Alignment tpr and PRSS2

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 99/242 - (40%)
• Similarity: 139/242 - (57%)
• Gaps: 20/242 - (8%)

  Fly   126 RIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCV----------YGFRKERISVR 180
            :||||...|.:..|: .:.|..|..:|..||:::|::::|.||.          .|....||.||
Human    23 KIVGGYICEENSVPY-QVSLNSGYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVR 86

  Fly   181 LLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKG 245
            |.||:.::....:.....|::|.|||||:|..||||.:|||..|...|..:..:.:||...: .|
Human    87 LGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPA-AG 150

  Fly   246 ENGIVTGWG-ALKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDS 309
            ...:::||| .|..|....|.||.:..|:|||.||..| |..|||:||.|.|:.|||||||||||
Human   151 TESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEAS-YPGKITNNMFCVGFLEGGKDSCQGDS 214

  Fly   310 GGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKN 356
            |||  :|::|    ::.|:||||.|||:...||||.:|..|..|||:
Human   215 GGP--VVSNG----ELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	98/239 (41%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	99/241 (41%)