Protein Alignment tpr and KLK15

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 92/250 - (36%)
• Similarity: 134/250 - (53%)
• Gaps: 30/250 - (12%)

  Fly   126 RIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHD-RKMS 189
            :::.|.|...|..||...|...|||.|.|||::..::|:|:||...|.:    |||.||: ||..
Human    21 KLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMR----VRLGEHNLRKRD 81

  Fly   190 HMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPT--PGRSFKGENGIVTG 252
            ..::: |..:.||.||:|.||::.|||.:::|.:|...|..:.|..:||  |   ..||..:|:|
Human    82 GPEQL-RTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCP---HPGEACVVSG 142

  Fly   253 WGALK------VGGPTS-----DTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQ 306
            ||.:.      .|.|.|     |||....:.|:|...|.|| |..::|:.|:|.|.:..|.:||:
Human   143 WGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKS-YPGRLTNTMVCAGAEGRGAESCE 206

  Fly   307 GDSGGPLHIVASGTREHQIAGVVSWGE-GCAKAGYPGVYARVNRYGTWIKNLTKQ 360
            |||||||  |..|.    :.|:||||: .|.....||||.:|..|..||:...|:
Human   207 GDSGGPL--VCGGI----LQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKR 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	91/243 (37%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	89/238 (37%)