DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tpr and prss27

DIOPT Version :9

Sequence 1:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	87/261 - (33%)
Similarity:	134/261 - (51%)	Gaps:	38/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 CGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCV-YGFRKERISVRL 181
            ||......|||||......::||...::|.....|..||::..::::|:||. ..::.|.:.|.|
Frog   411 CGQPAFSDRIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSSNWVVSAAHCFPRSYKIENMQVLL 475

  Fly   182 -------LEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTP 239
                   |..|       .:..:|..|||:|.|.......|||:::::.||.::..:.|:|:|..
Frog   476 GCFALMNLTSD-------AVIIRVKRVITYPLYTGEGSSGDIAMVEMESPVTYSSYILPICIPLT 533

  Fly   240 GRSF-KGENGIVTGWGALKVGGPTSDT-------LQEVQVPILSQDECRKSRYGNK--------I 288
            ...| .|:...|||||.::     ||.       ||||:||:::...|....:.|.        :
Frog   534 NEDFPSGKMCWVTGWGNIQ-----SDVSLSPPYPLQEVEVPLVNASSCDTMYHYNSDLNPATQLV 593

  Fly   289 TDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTW 353
            .|:|:|.||.||.||:||||||||| ...||.... :.|:||||:|||:...||||.:|:.:.:|
Frog   594 HDDMICAGYPEGQKDACQGDSGGPL-ACKSGNYWF-LTGIVSWGDGCAQPNRPGVYTKVSSFSSW 656

  Fly   354 I 354
            |
Frog   657 I 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	83/251 (33%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	84/252 (33%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	84/252 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3837
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.970