Protein Alignment tpr and ACR

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 87/272 - (31%)
• Similarity: 128/272 - (47%)
• Gaps: 44/272 - (16%)

  Fly   115 DCVCGIANIQK-----RIVGGQETEVHQYPWVAML---LYGGRFY--CAASLLNDQFLLTASHCV 169
            |..||:...|.     |||||:..:...:||:..|   .|....|  |..||||.:::|||:||.
Human    26 DGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCF 90

  Fly   170 YGFRKERISVRLLEHDRKMSHMQK--------------IDRKVAEVITHPKYNARNYDNDIAIIK 220
            .|  |..:      ||.::....|              .:|.|.::|.|.|||:....||||:::
Human    91 VG--KNNV------HDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVE 147

  Fly   221 LDEPVEFNEVLHPVCMPTPGRSFK------GENGIVTGWGALKVGGP-TSDTLQEVQVPILSQDE 278
            :..|:.....:.|.|:|    .||      .::..|.|||.::...| .|..|.|.:|.::..|.
Human   148 ITPPISCGRFIGPGCLP----HFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDL 208

  Fly   279 CRKSR-YGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPG 342
            |..:: |..::....:|.||..|..|:|||||||||....|....:.:.|:.|||.|||:|..||
Human   209 CNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPG 273

  Fly   343 VYARVNRYGTWI 354
            :|.....|..||
Human   274 IYTATWPYLNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	82/255 (32%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	81/254 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421