Protein Alignment tpr and KLK14

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 93/243 - (38%)
• Similarity: 137/243 - (56%)
• Gaps: 30/243 - (12%)

  Fly   124 QKRIVGGQETEVHQYPWVAMLLYG--GRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHD- 185
            :.:|:||........||.|.||.|  .||.|..:||:.|:::||:||    .:..:.|.|.:|:
Human    22 ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHC----GRPILQVALGKHNL 82

  Fly   186 RKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPV----CMPTPGRSFKGE 246
            |:....|::.|.|.:| |||.||:|.:|||:.:::|.:|......:.|:    ...:||.|.:
Human    83 RRWEATQQVLRVVRQV-THPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCR-- 144

  Fly   247 NGIVTGWGALKVGGPTS---DTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGD 308
               |:|||.  :..|.:   .:||.|.:.|...:.|:|: |...||..|:|.|..:|||||||||
Human   145 ---VSGWGT--ISSPIARYPASLQCVNINISPDEVCQKA-YPRTITPGMVCAGVPQGGKDSCQGD 203

  Fly   309 SGGPLHIVASGTREHQIAGVVSWG-EGCAKAGYPGVYARVNRYGTWIK 355
            |||||  |..|    |:.|:|||| |.||..||||||..:.:|.:||:
Human   204 SGGPL--VCRG----QLQGLVSWGMERCALPGYPGVYTNLCKYRSWIE 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	93/240 (39%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	93/240 (39%)