DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tpr and CG11836

DIOPT Version :9

Sequence 1:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	114/256 - (44%)
Similarity:	167/256 - (65%)	Gaps:	7/256 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 RNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKE 175
            :|| ||.||.:|.:.|||||:.|.|:||||:|.::|.|:|:|..|||...::|:|:|||...||.
  Fly    82 KNC-DCDCGFSNEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKS 145

  Fly   176 RISVRLLEHDRKM-SHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTP 239
            :|.|...:||::: |..|.|.|.|..||.|..::...|:||||:::|.:|:.|::::.|:|:|..
  Fly   146 KIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRY 210

  Fly   240 GRSFKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRY-GNKITDNMLCGGYDEGGKD 303
            .....|..|.|.|||....||.....:.:|:|||:|..|||..|| ..:||.:|||.|  ....|
  Fly   211 NYDPAGRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAG--RPSMD 273

  Fly   304 SCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLTKQACLC 364
            |||||||||| ::::|.: :.|.|:||||.||.:.||||||:||:::..|||:..:..|||
  Fly   274 SCQGDSGGPL-LLSNGVK-YFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNLENTCLC 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	101/229 (44%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	102/230 (44%)
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	103/231 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471769
Domainoid	1	1.000	147	1.000	Domainoid score	I2768
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I2933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D19085at50557
OrthoFinder	1	1.000	-	-		FOG0001240
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	10	9.900