Protein Alignment tpr and Klk4

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001004101.1
• Gene: Klk4 / 408210
• RGDID: 1303228
• Length: 256
• Species: Rattus norvegicus
• Alignment Length: 243
• Identity: 84/243 - (34%)
• Similarity: 128/243 - (52%)
• Gaps: 28/243 - (11%)

  Fly   121 ANIQKRIVGGQETEVHQYPWVAMLL-YGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEH 184
            ::|..||:.||:...|..||.|.|. ....|:|:..|::.|::|:|:||:    ::..:|.|..|
  Rat    26 SSISSRIIQGQDCLPHSQPWQAALFSEDNAFFCSGVLVHPQWVLSAAHCI----QDSYTVGLGLH 86

  Fly   185 DRKMSHMQKIDRKVAEV---ITHPKYNARNYDNDIAIIKLDEPV-EFNEVLH-PVC--MPTPGRS 242
            :.:.|  |:...::.|.   |.||.||..::.||:.:|||:|.| |.|.:.. ||.  .|||
  Rat    87 NLEGS--QEPGSRMLEAHLSIQHPNYNDPSFANDLMLIKLNESVMESNTIRRIPVASQCPTP--- 146

  Fly   243 FKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQG 307
              |:..:|:|||.|| .|.....||.|.:.:.|::.|| ..|......:|.|.|.....||:|.|
  Rat   147 --GDTCLVSGWGRLK-NGKLPSLLQCVNLSVASEETCR-LLYDPVYHLSMFCAGGGPDRKDTCNG 207

  Fly   308 DSGGPLHIVASGTREHQIAGVVSWGEG-CAKAGYPGVYARVNRYGTWI 354
            |||||  ||.:    ..:.|:||.|:| |.:.|.|.||..:.::..||
  Rat   208 DSGGP--IVCN----RSLQGLVSMGQGECGQPGIPSVYTNLCKFTNWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	82/237 (35%)
Klk4	NP_001004101.1	Tryp_SPc	35..249	CDD:238113	79/232 (34%)