Protein Alignment tpr and PRSS57

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_999875.2
• Gene: PRSS57 / 400668
• HGNCID: 31397
• Length: 283
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 73/251 - (29%)
• Similarity: 118/251 - (47%)
• Gaps: 33/251 - (13%)

  Fly   126 RIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMSH 190
            :|:||.|...|..|::|.:.:||:.:|...||..:::::|:|| :..|..|..:.:|.     :|
Human    33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHC-FSHRDLRTGLVVLG-----AH 91

  Fly   191 MQKIDRKVAEVI------THPKYNARNYDNDIAIIKLDEPVEFNEVLHPV--CMPTPGRSFK--- 244
            :........:|.      |||.|:...:.|||.:::|:.    :.||.|.  .:..|||..:
Human    92 VLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNG----SAVLGPAVGLLRPPGRRARPPT 152

  Fly   245 -GENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLC--GGYDEGGKDSCQ 306
             |....|.|||.:.........|.|.:|.:|..|.|..|..|: :|..|||  .| |...:..|.
Human   153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSG-DSHRRGFCS 215

  Fly   307 GDSGGPLHIVASGTREHQIAGVVSW-GEGCAKAGYPGVYARVNRYGTWIKNLTKQA 361
            .||||||   ....|.|   |:||: |..|.....|.||.:|:.:..||.::.:::
Human   216 ADSGGPL---VCRNRAH---GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	73/243 (30%)
PRSS57	NP_999875.2	Tryp_SPc	34..258	CDD:238113	71/241 (29%)