Protein Alignment tpr and PRSS41

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001382429.1
• Gene: PRSS41 / 360226
• HGNCID: 30715
• Length: 334
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 85/264 - (32%)
• Similarity: 129/264 - (48%)
• Gaps: 38/264 - (14%)

  Fly   118 CGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRK----ERIS 178
            ||...|...:.||.|:...::||.|.|....|..|..|||:.:::|:|:||   |:|    ...:
Human    62 CGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHC---FQKHYYPSEWT 123

  Fly   179 VRLLEHDRKMS----HMQKIDRKVAEVITHPKYNARNYD------NDIAIIKLDEPVEFNEVLHP 233
            |:|.|...:.:    .......||.::|.:|       |      ||||:::|...|.:|..:.|
Human   124 VQLGELTSRPTPWNLRAYSSRYKVQDIIVNP-------DALGVLRNDIALLRLASSVTYNAYIQP 181

  Fly   234 VCMPTPGRSFKGENGI-VTGWGALKVGG---PTSDTLQEVQVPILSQDECR------KSRYGNKI 288
            :|:.:...:|...... |||||.:...|   |....|:|.||.||:...|.      .||  :.|
Human   182 ICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSR--SMI 244

  Fly   289 TDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTW 353
            .|:|.|.|.::|..|:|:|||||||.....|. .:|: |:||||..|.:...||||..::.|..|
Human   245 WDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGL-WYQV-GIVSWGMDCGQPNRPGVYTNISVYFHW 307

  Fly   354 IKNL 357
            |:.:
Human   308 IRRV 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	82/252 (33%)
PRSS41	NP_001382429.1	Tryp_SPc	71..311	CDD:238113	82/253 (32%)