Protein Alignment tpr and TMPRSS9

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 100/284 - (35%)
• Similarity: 149/284 - (52%)
• Gaps: 26/284 - (9%)

  Fly    98 RATTPAPPTLNPPRNCSD------CVCGIA---NIQKRIVGGQETEVHQYPWVAMLLYGGRFYCA 153
            :..|...|..:...:|||      |.||:.   .:..|||||.|....::||.|.|......:|.
Human   199 QCVTKVNPECDDQEDCSDGSDEAHCECGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCG 263

  Fly   154 ASLLNDQFLLTASHCVYGFRKER-----ISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYD 213
            |:::|.::|::|:||...|:...     :....|..    |....:..:|.:::.||.|||...|
Human   264 AAIINARWLVSAAHCFNEFQDPTKWVAYVGATYLSG----SEASTVRAQVVQIVKHPLYNADTAD 324

  Fly   214 NDIAIIKLDEPVEFNEVLHPVCMPTPGRSF-KGENGIVTGWGALK---VGGPTSDTLQEVQVPIL 274
            .|:|:::|..|:.|...:.|||:|.....| ..:..:::|||.||   :..|  :.||:..|.:|
Human   325 FDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKP--EVLQKATVELL 387

  Fly   275 SQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAG 339
            .|..| .|.||:.:||.|:|.||.:|..||||||||||| :....:....:||:||||.|||:|.
Human   388 DQALC-ASLYGHSLTDRMVCAGYLDGKVDSCQGDSGGPL-VCEEPSGRFFLAGIVSWGIGCAEAR 450

  Fly   340 YPGVYARVNRYGTWIKNLTKQACL 363
            .|||||||.|...||...|.:|.:
Human   451 RPGVYARVTRLRDWILEATTKASM 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	89/237 (38%)
TMPRSS9	NP_001382442.1	SEA	66..>127	CDD:460188
		LDLa	188..223	CDD:238060	5/23 (22%)
		Tryp_SPc	236..465	CDD:214473	88/236 (37%)
		Tryp_SPc	538..768	CDD:238113
		Pneumo_att_G	<717..>867	CDD:114270
		Tryp_SPc	861..1087	CDD:238113