DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tpr and flz

DIOPT Version :9

Sequence 1:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	131/483 - (27%)
Similarity:	195/483 - (40%)	Gaps:	142/483 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LALSCGPSQSASQ-DRATNQTAASPLLKQSQNTFIQWVLSLLP----------QRPGSSDSENAT 65
            |.:|...|...|. |.:|.......:||...:|.:..:::.|.          :.|||    |.|
  Fly  1214 LNMSAASSAVTSDLDLSTPAFVEDVVLKDKMHTLVHKLVASLQGNFEALADMIEEPGS----NKT 1274

  Fly    66 LATLSS------------SSMMPDAASTTS------------TTTPAPSSST----TTTRR---- 98
            :||..:            ::..|...:||:            .||.||:..|    ||||:
  Fly  1275 VATYQAGAGGTAKPVRVVTTRKPVRTATTTRPKVTTKKPVTRVTTKAPNKKTSAVSTTTRKPATR 1339

  Fly    99 ---------ATTPAPPTLNPPRNCSDCV------------------------------------- 117
                     .||..|.|..|.|..|..|
  Fly  1340 RTTVAAKVTTTTRRPATKKPTRRVSSTVKTTTVSSARPADDEIVDEEDEEDVNPNPSDNEIDQGA 1404

  Fly   118 ---------------------------------CGIANIQK--RIVGGQETEVHQYPWVAML--- 144
                                             ||:....|  |||||:.:....|||..::
  Fly  1405 TLSSYGGANGRKIHSTSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRES 1469

  Fly   145 LYGGRF---YCAASLLNDQFLLTASHCVYGFRKERISVRLLEHD--RKMSHMQKIDRKVAEVITH 204
            .:.|.|   .|...|:..::::||:||..||....::| :.|.|  ..:...:.:.:.|..||.|
  Fly  1470 TWLGLFTKNKCGGVLITSRYVITAAHCQPGFLASLVAV-MGEFDISGDLESKRSVTKNVKRVIVH 1533

  Fly   205 PKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKGENGIVTGWGALKVGGPTSDTLQEV 269
            .:|:...::||:|:::||.||:|:..:.|:|||.....|.|....|||||.||.||.....||||
  Fly  1534 RQYDPATFENDLALLELDSPVQFDTHIVPICMPNDVADFTGRMATVTGWGRLKYGGGVPSVLQEV 1598

  Fly   270 QVPILSQDECRK----SRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVS 330
            ||||:....|::    :.:..||..:.||.||..|.||||:||||||| ::......:::||.||
  Fly  1599 QVPIIENSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPL-VLQRPDGRYELAGTVS 1662

  Fly   331 WGEGCAKAGYPGVYARVNRYGTWIKNLT 358
            .|..||....||||.|...|..|::::|
  Fly  1663 HGIKCAAPYLPGVYMRTTFYKPWLRSIT 1690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	89/239 (37%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	89/240 (37%)
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	89/241 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457806
Domainoid	1	1.000	147	1.000	Domainoid score	I2768
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840