Protein Alignment tpr and KLK3

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 81/252 - (32%)
• Similarity: 124/252 - (49%)
• Gaps: 35/252 - (13%)

  Fly   123 IQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRK 187
            |..|||||.|.|.|..||..::...||..|...|::.|::|||:||:    :.:..:.|..|  .
Human    21 ILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI----RNKSVILLGRH--S 79

  Fly   188 MSHMQKIDR--KVAEVITHPKYNARNYDN-----------DIAIIKLDEPVEFNEVLHPVCMPTP 239
            :.|.:...:  :|:....||.|:.....|           |:.:::|.||.|..:.:..:.:||.
Human    80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144

  Fly   240 GRSFKGENGIVTGWGALKVGGP----TSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEG 300
            ..:. |.....:|||:::   |    |...||.|.:.::|.|.|.:. :..|:|..|||.|...|
Human   145 EPAL-GTTCYASGWGSIE---PEEFLTPKKLQCVDLHVISNDVCAQV-HPQKVTKFMLCAGRWTG 204

  Fly   301 GKDSCQGDSGGPLHIVASGTREHQIAGVVSWG-EGCAKAGYPGVYARVNRYGTWIKN 356
            ||.:|.|||||||  |.:|.    :.|:.||| |.||....|.:|.:|..|..|||:
Human   205 GKSTCSGDSGGPL--VCNGV----LQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	78/246 (32%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	79/248 (32%)