DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tpr and l(2)k05911

DIOPT Version :9

Sequence 1:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_723797.3	Gene:	l(2)k05911 / 34731	FlyBaseID:	FBgn0284244	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	127/371 - (34%)
Similarity:	180/371 - (48%)	Gaps:	54/371 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PLLKQSQNTF--IQWVLS---------LLPQRPGSSDSENATLATLSSSSMMPDAAST-----TS 83
            |:..|..:|.  .||...         .||..|.::......|.|...:...|...:|     |.
  Fly   274 PISTQPASTIHPYQWPFGSFAGGQWPPALPTHPPTTGGWPPPLPTHPPNHHYPTHPTTGGVPSTK 338

  Fly    84 TTTPAPSSST--TTTRRATTPAPP--------TLNPPRNCSD----CVCGIAN----IQKRIVGG 130
            .|||.|:|..  |||||.|.|:.|        |..|....|.    ..||..|    .|:|||||
  Fly   339 RTTPRPTSPARPTTTRRPTYPSYPSPVTTTTTTRRPVSGTSSEGLPLQCGNKNPVTPDQERIVGG 403

  Fly   131 QETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEH--DRKMS---H 190
            .....|::||:|:|...|:.:|..||:.:..:|||:|||.......::. |..|  |..:.   .
  Fly   404 INASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCVARMTSWDVAA-LTAHLGDYNIGTDFE 467

  Fly   191 MQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPT----PGRSFKGENGIVT 251
            :|.:.|::..::.|..:......||:||:.|.|||.|...:.|:|:||    ..||:.|:...|.
  Fly   468 VQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTREIQPICLPTSPSQQSRSYSGQVATVA 532

  Fly   252 GWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNK----ITDNMLCGGYDEGGKDSCQGDSGGP 312
            |||:|:..||....||:|.:||.:..||.: :||..    |.::|:|.|  :..||||.||||||
  Fly   533 GWGSLRENGPQPSILQKVDIPIWTNAECAR-KYGRAAPGGIIESMICAG--QAAKDSCSGDSGGP 594

  Fly   313 LHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI-KNL 357
            : ::..|.|..|: |:||||.||.|..|||||.||.....|| ||:
  Fly   595 M-VINDGGRYTQV-GIVSWGIGCGKGQYPGVYTRVTSLLPWIYKNI 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	90/240 (38%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	91/242 (38%)
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		Tryp_SPc	399..634	CDD:214473	90/240 (38%)
		Tryp_SPc	400..637	CDD:238113	91/242 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	147	1.000	Domainoid score	I2768
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	5	4.910