Protein Alignment tpr and OVCH2

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_047282834.1
• Gene: OVCH2 / 341277
• HGNCID: 29970
• Length: 569
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 86/277 - (31%)
• Similarity: 135/277 - (48%)
• Gaps: 34/277 - (12%)

  Fly   106 TLNPPR--NCSDCVCGIA-----NIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLL 163
            ||:.|:  :|...:..:.     ||..||:||.:.|...|||...|....:..|..|:::.|:::
Human    28 TLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVI 92

  Fly   164 TASHCVYGFR-KERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARN-YDNDIAIIKLDEPVE 226
            ||:||:.... ...::|...|:|...:...:....:..||.||.::.:. .|.|||::|:....:
Human    93 TAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQ 157

  Fly   227 FNEVLHPVCMPTPGRSFKGENGIV---TGWGALKVGGPTSDTLQEVQVPILSQDEC------RKS 282
            |...:.|:|:|.....|  |.|.:   .|||.|..||..|..||||.:|||:.:||      .|.
Human   158 FGHFVGPICLPELREQF--EAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKR 220

  Fly   283 RYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKA--------- 338
            ....|   ..||.|:.:||:|:|||||||.| :..:......:|||.|||.||.:.
Human   221 PISGK---TFLCTGFPDGGRDACQGDSGGSL-MCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSD 281

  Fly   339 -GYPGVYARVNRYGTWI 354
             |.||::..:::...||
Human   282 QGSPGIFTDISKVLPWI 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	79/249 (32%)
OVCH2	XP_047282834.1	Tryp_SPc	56..301	CDD:238113	79/249 (32%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001