Protein Alignment tpr and PRSS38

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_898885.1
• Gene: PRSS38 / 339501
• HGNCID: 29625
• Length: 326
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 91/273 - (33%)
• Similarity: 136/273 - (49%)
• Gaps: 31/273 - (11%)

  Fly   103 APPTL-----NPPRN-----CSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLL 157
            |||.:     ..|.|     .....||..:::.:|:||......::||...:.|.|...|..|:|
Human    26 APPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSIL 90

  Fly   158 NDQFLLTASHC--------VYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARN-YD 213
            |:.::|:|:||        :|......:::|:..     :|.|..:  |..||.||.|...: ..
Human    91 NEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAG-----NHTQWYE--VNRVILHPTYEMYHPIG 148

  Fly   214 NDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDE 278
            .|:|:::|...:.|:|.:.|||:.||..:....|...||||.:...|.|||.|||:|:|::.:..
Human   149 GDVALVQLKTRIVFSESVLPVCLATPEVNLTSANCWATGWGLVSKQGETSDELQEMQLPLILEPW 213

  Fly   279 CRKSRYGNK--ITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYP 341
            |. ..||:.  |..:|||.|.....|..|:|||||||  |....|.....|:||||.||:...||
Human   214 CH-LLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPL--VCEFNRSWLQIGIVSWGRGCSNPLYP 275

  Fly   342 GVYARVNRYGTWI 354
            ||||.|:.:..||
Human   276 GVYASVSYFSKWI 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	84/239 (35%)
PRSS38	NP_898885.1	Tryp_SPc	60..291	CDD:238113	84/239 (35%)