Protein Alignment tpr and HPN

DIOPT Version :9

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001362370.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 99/265 - (37%)
• Similarity: 136/265 - (51%)
• Gaps: 37/265 - (13%)

  Fly   113 CSDCVCGIANIQ-KRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKER 176
            |.|  ||...:. .|||||::|.:.::||...|.|.|...|..|||:..::|||:||
Human   150 CQD--CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-------- 204

  Fly   177 ISVRLLEHDRKMSHMQKIDRKVAE------------VITHPKY------NARNYDNDIAIIKLDE 223
                ..|.:|.:|..:.....||:            |:.|..|      |:....||||::.|..
Human   205 ----FPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSS 265

  Fly   224 PVEFNEVLHPVCMPTPGRSF-KGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSR-YGN 286
            |:...|.:.|||:|..|::. .|:...|||||..:..|..:..|||.:|||:|.|.|..:. |||
Human   266 PLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGN 330

  Fly   287 KITDNMLCGGYDEGGKDSCQGDSGGPL--HIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNR 349
            :|...|.|.||.|||.|:||||||||.  ....|.|...::.|:||||.|||.|..||||.:|:.
Human   331 QIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSD 395

  Fly   350 YGTWI 354
            :..||
Human   396 FREWI 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	93/249 (37%)
		Tryp_SPc	127..356	CDD:238113	94/250 (38%)
HPN	NP_001362370.1	Hepsin-SRCR	51..159	CDD:401275	4/10 (40%)
		Tryp_SPc	163..400	CDD:238113	92/248 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	175	1.000	Inparanoid score	I4057
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8579
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.960