Protein Alignment tpr and Tmprss11b

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_795998.2
• Gene: Tmprss11b / 319875
• MGIID: 2442893
• Length: 416
• Species: Mus musculus
• Alignment Length: 352
• Identity: 114/352 - (32%)
• Similarity: 163/352 - (46%)
• Gaps: 56/352 - (15%)

  Fly    39 QSQNTFIQW----VLSLLPQ------------RPGSSDSENATLATLSSSSMMPDAASTTSTTTP 87
            |:.|.:.|:    |::|:|.            :...|:.||......|....|.:....:.||.|
Mouse    87 QNSNIYKQYINSQVITLVPDNNSVTAHIWLVFKDPWSNKENLRRRIESILRQMLENNPESLTTDP 151

  Fly    88 APSSSTTTTRRATTPAPPTLNPPRNCSDCVCG----IANIQKRIVGGQETEVHQYPWVAMLLYGG 148
               .|...|..:...|...:|..       ||    ::....||.||......::||.|.|...|
Mouse   152 ---GSLKLTEISKVDAEKIINNR-------CGRRPRMSATYDRITGGSTAHKGEWPWQASLRVNG 206

  Fly   149 RFYCAASLLNDQFLLTASHCVYGFRK---------ERISVRLLEHDRKMSHMQKIDRKVAEVITH 204
            :.||.|||:.::|||||:||..|...         .|::...::|            .|.|:|.|
Mouse   207 KHYCGASLIGERFLLTAAHCFQGTNNPKNLTVSFGTRVTPAYMQH------------SVQEIIIH 259

  Fly   205 PKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSF-KGENGIVTGWGALKVGGPTSDTLQE 268
            ..|....:.:|:|:|||.|.|.||..:|.||:|...:.| .||..:|||||:....|.:...||:
Mouse   260 EDYVKGEHHDDVAVIKLTEKVSFNNDVHRVCLPESTQIFPPGEGVVVTGWGSFSYNGKSPLLLQK 324

  Fly   269 VQVPILSQDECR-KSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTRE-HQIAGVVSW 331
            ..:.|:..:.|. :..||.:|.|.|||.||.||..|:|||||||||  |...:|: ..:.|:|||
Mouse   325 ASIKIIDTNTCNSEEAYGGRIVDTMLCAGYLEGSIDACQGDSGGPL--VHPNSRDIWYLVGIVSW 387

  Fly   332 GEGCAKAGYPGVYARVNRYGTWIKNLT 358
            |..|.:...||||.||..|..||.:.|
Mouse   388 GHECGRVNKPGVYMRVTSYRNWIASKT 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	92/240 (38%)
Tmprss11b	NP_795998.2	SEA	46..143	CDD:460188	11/55 (20%)
		Tryp_SPc	185..413	CDD:238113	92/241 (38%)