DRSC/TRiP Functional Genomics Resources

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Protein Alignment tpr and Tmprss6

DIOPT Version :9

Sequence 1:NP_611611.1 Gene:tpr / 37486 FlyBaseID:FBgn0034661 Length:372 Species:Drosophila melanogaster
Sequence 2:XP_006242057.1 Gene:Tmprss6 / 315388 RGDID:1307138 Length:811 Species:Rattus norvegicus


Alignment Length:266 Identity:100/266 - (37%)
Similarity:155/266 - (58%) Gaps:18/266 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   105 PTLNPPRNCSD------CVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLL 163
            |..:...:|.|      |.||:.....|||||..:...::||.|.|...||..|..:|:.|::::
  Rat   549 PECDGQADCRDGSDEEHCDCGLQGPSSRIVGGAMSSEGEWPWQASLQIRGRHICGGALIADRWVI 613

  Fly   164 TASHCVYGFRKERI-SVRL----LEHDRKMSHMQ-KIDRKVAEVITHPKYNARNYDNDIAIIKLD 222
            ||:||   |:::.: |.||    |...|:.|... ::..||:.:..||.:...::|.|:|:::||
  Rat   614 TAAHC---FQEDSMASPRLWTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLD 675

  Fly   223 EPVEFNEVLHPVCMPTPGRSFK-GENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGN 286
            .||.::..:.|||:|.....|: |::..:|||||.:.|||.|.|||:|.|.::.||.|.:: |..
  Rat   676 HPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREGGPGSSTLQKVDVQLIPQDLCNEA-YRY 739

  Fly   287 KITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYG 351
            ::|..|||.||.:|.||:||||||||| :....:....:||:||||.||.:..:.|||.||.|..
  Rat   740 QVTPRMLCAGYRKGKKDACQGDSGGPL-VCKEPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVV 803

  Fly   352 TWIKNL 357
            .||:.:
  Rat   804 NWIQQV 809

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tprNP_611611.1 Tryp_SPc 126..354 CDD:214473 92/234 (39%)
Tryp_SPc 127..356 CDD:238113 93/235 (40%)
Tmprss6XP_006242057.1 SEA 88..185 CDD:279699
LDLa 459..489 CDD:238060
LDLa 495..525 CDD:238060
Ldl_recept_a 529..566 CDD:278486 3/16 (19%)
Tryp_SPc 576..806 CDD:214473 92/234 (39%)
Tryp_SPc 577..809 CDD:238113 93/236 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BJ04
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100031
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X11
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.710

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