DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tpr and Tmprss3

DIOPT Version :9

Sequence 1:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	95/251 - (37%)
Similarity:	135/251 - (53%)	Gaps:	19/251 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 CSDCVCGI-ANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGF---R 173
            ||  .||: .....|||||..:.:.|:||...|.:.|...|..|::...:::||:||||..   :
  Rat   204 CS--ACGMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGYHLCGGSVITPLWIVTAAHCVYDLYHPK 266

  Fly   174 KERISVRL--LEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCM 236
            ...:.|.|  |......||:      |.::|.|.||..:...||||::||.||:.|:|.:.|:|:
  Rat   267 SWTVQVGLVSLMDSPVPSHL------VEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICL 325

  Fly   237 PTPGRSF-KGENGIVTGWGALKVG-GPTSDTLQEVQVPILSQDEC-RKSRYGNKITDNMLCGGYD 298
            |....:| .|:....:||||.:.| |..|..|....||::|...| .:..||..|:.:|||.||.
  Rat   326 PNSEENFPDGKLCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYL 390

  Fly   299 EGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI 354
            :||.|||||||||||  |....|..::.|..|:|.|||:...||||.|:..:..||
  Rat   391 KGGVDSCQGDSGGPL--VCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWI 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	89/235 (38%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	90/236 (38%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	4/8 (50%)
		Tryp_SPc	216..444	CDD:214473	89/235 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.860