Protein Alignment tpr and Prss22

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001100454.1
• Gene: Prss22 / 302971
• RGDID: 1310880
• Length: 307
• Species: Rattus norvegicus
• Alignment Length: 283
• Identity: 92/283 - (32%)
• Similarity: 154/283 - (54%)
• Gaps: 31/283 - (10%)

  Fly    91 SSTTTTRRATTPAPPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAAS 155
            :||.|...|.....|.           ||......|:|||:::...|:||:..:|..|..:||.|
  Rat    25 TSTATVSAANIRGSPD-----------CGKPQQLNRVVGGEDSADAQWPWIVSILKNGSHHCAGS 78

  Fly   156 LLNDQFLLTASHCVYGFRKERISVRLLEHDRKMSH----MQKIDRKVAEVITHPKYNARNYDN-D 215
            ||.::::::|:||......:.....:|....|:.:    .||:.  :|.|:.||:|:.:...: |
  Rat    79 LLTNRWVVSAAHCFSSNMDKPSPYSVLLGAWKLGNPGPRSQKVG--IASVLPHPRYSRKEGTHAD 141

  Fly   216 IAIIKLDEPVEFNEVLHPVCMPTPGRSF-KGENGIVTGWGALKVGG--PTSDTLQEVQVPILSQD 277
            ||:::|:.|::|:|.:.|:|:|...... ...|..:.|||:::.|.  |...|||:::|||:..:
  Rat   142 IALVRLERPIQFSERILPICLPDSSVHLPPNTNCWIAGWGSIQDGVPLPRPQTLQKLKVPIIDPE 206

  Fly   278 ECRKSRY----GNK-ITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREH-QIAGVVSWGEGCA 336
            .| ||.|    |.: ||::|||.||.||.:|:|.|||||||.....   :| .:.|::|||||||
  Rat   207 LC-KSLYWRGAGQEAITEDMLCAGYLEGKRDACLGDSGGPLMCQVD---DHWLLTGIISWGEGCA 267

  Fly   337 KAGYPGVYARVNRYGTWIKNLTK 359
            :...||||..:..:..|::.:.:
  Rat   268 ERNRPGVYTSLLAHRPWVQRIVQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	84/242 (35%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	84/243 (35%)