Protein Alignment tpr and GZMK

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 89/249 - (35%)
• Similarity: 126/249 - (50%)
• Gaps: 22/249 - (8%)

  Fly   117 VCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRK-ERISVR 180
            ||    ....|:||:|...|..|::|.:.|||...|...|::.|::|||:||.|.|.| :..:|.
Human    21 VC----FNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVV 81

  Fly   181 LLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFN---EVLHPVCMPTPGRS 242
            |..|....:...|...::.:.|...:..:....|||.::||....:.|   ::|| :...|..||
Human    82 LGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLH-IRSKTSLRS 145

  Fly   243 FKGENGIVTGWGALKVGG-PTSDTLQEVQVPILSQDECRKSRYGNK---ITDNMLCGGYDEGGKD 303
              |....||||||..... ..||||:||.|.:||:..|....|.|.   ||.:|:|.|..:|.||
Human   146 --GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKD 208

  Fly   304 SCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARV-NRYGTWIKN 356
            ||:|||||||  :..|.    ...:||.|..|..|..||:|..: .:|.||||:
Human   209 SCKGDSGGPL--ICKGV----FHAIVSGGHECGVATKPGIYTLLTKKYQTWIKS 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	86/237 (36%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	87/239 (36%)