Protein Alignment tpr and GZMA

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_006135.2
• Gene: GZMA / 3001
• HGNCID: 4708
• Length: 262
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 72/240 - (30%)
• Similarity: 113/240 - (47%)
• Gaps: 16/240 - (6%)

  Fly   122 NIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDR 186
            ::.::|:||.|...|..|::.:|....:..||.:|:...::|||:||..   .:|..|.|..|..
Human    24 DVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNL---NKRSQVILGAHSI 85

  Fly   187 KMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFK-GENGIV 250
            ......|....|.:...:|.|:....:.|:.:::|.|..:.|:.:..:.:|..|...| |....|
Human    86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQV 150

  Fly   251 TGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGN---KITDNMLCGGYDEGGKDSCQGDSGGP 312
            .|||........||||:||.:.|:.:..|....:.|   .|..||:|.|...||:|||.||||.|
Human   151 AGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSP 215

  Fly   313 LHIVASGTREHQIAGVVSWG--EGCAKAGYPGVYARVN-RYGTWI 354
            |  :..|.    ..||.|:|  ..|.....||||..:: ::..||
Human   216 L--LCEGV----FRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	72/235 (31%)
GZMA	NP_006135.2	Tryp_SPc	29..254	CDD:238113	70/233 (30%)