Protein Alignment tpr and F10

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_058839.1
• Gene: F10 / 29243
• RGDID: 61850
• Length: 482
• Species: Rattus norvegicus
• Alignment Length: 340
• Identity: 107/340 - (31%)
• Similarity: 168/340 - (49%)
• Gaps: 44/340 - (12%)

  Fly    49 LSLLPQRPGSSDSENA--TLATLSSSS------MMPDAASTTSTTTPAPSSSTTTTRRATTPAPP 105
            ||..|...|.::...|  ::|..:|:|      :||||.....|.:|:...:...|
  Rat   165 LSTAPFPCGKTNKGRAKRSVALNTSNSEPDPEDLMPDADILYPTESPSELLNLNKT--------- 220

  Fly   106 TLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRF--YCAASLLNDQFLLTASHC 168
              .|..|..|.:        |||||||.:..:.||.|:|......  :|..::||:.::|||:||
  Rat   221 --EPEANSDDVI--------RIVGGQECKRGECPWQALLFSDEETDGFCGGTILNEFYILTAAHC 275

  Fly   169 VYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHP 233
            ::  :.:|..||:.:.:.:.....::..:|..:|.|.|:....||.|||:::|..|:.|.|.:.|
  Rat   276 LH--QAKRFKVRVGDLNTEQEDGGEMVHEVDMIIKHNKFQRDTYDFDIAMLRLKTPITFRENVAP 338

  Fly   234 VCMP----TPGRSFKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLC 294
            .|:|    ........:.|||:|:|.....|..|..|:.::||.:.::.||.|. ...||.||.|
  Rat   339 ACLPQKDWAEATLMTQKTGIVSGFGRTHEKGRQSKVLKMMEVPYVDRNTCRLST-SFSITQNMFC 402

  Fly   295 GGYDEGGKDSCQGDSGGPLHIVASGTR---EHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKN 356
            .|||...:|:|||||||| |:    ||   .:.:.|:||||||||:.|..|:|.:|..:..||..
  Rat   403 AGYDAKQEDACQGDSGGP-HV----TRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDR 462

  Fly   357 LTKQACLCQQETKKI 371
            ..|.......||.::
  Rat   463 SMKARVGPTSETPRL 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	85/237 (36%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		Tryp_SPc	232..462	CDD:238113	85/237 (36%)