Protein Alignment tpr and Habp2

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001001505.2
• Gene: Habp2 / 292126
• RGDID: 1302979
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 294
• Identity: 91/294 - (30%)
• Similarity: 147/294 - (50%)
• Gaps: 42/294 - (14%)

  Fly   102 PAPPTLNPPRNCSDCV--------CGIANIQ----KRIVGGQETEVHQYPWVAML---------L 145
            |.....||..:..:.|        ||...:.    |||.||.::...::||...|         :
  Rat   275 PESDAANPLGSLQEPVMELPGFDSCGKTEMTEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSM 339

  Fly   146 YGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNAR 210
            ..|.| |..||::..::|||:||. ....:.:.|.|.:.|.|.:...:...:|.:::.:.:||.|
  Rat   340 PQGHF-CGGSLIHPCWVLTAAHCT-DMSTKHLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNER 402

  Fly   211 NY--DNDIAIIKLDEPVE-----FNEVLHPVCMPT-PGRSFKGENGIVTGWGALKVGGPTSDTLQ 267
            :.  .||||::|| :||.     .::.:..||:|: |..|  |....::|||..:. |..|..|.
  Rat   403 DEIPHNDIALLKL-KPVGGHCALESKYVKTVCLPSDPFPS--GTECHISGWGVTET-GEGSRQLL 463

  Fly   268 EVQVPILSQDECR-KSRYGNKITDNMLC-GGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVS 330
            :.:|.:::...|. :..|.:.|.|:|:| |...:.|.|:|||||||||.....||  :.:.|:||
  Rat   464 DAKVKLIANALCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGT--YYVYGIVS 526

  Fly   331 WGEGCAKAGYPGVYARVNRYGTWIK-NLTKQACL 363
            ||:.|.|.  ||||.:|.::..||| .:.|:|.|
  Rat   527 WGQECGKK--PGVYTQVTKFLNWIKTTMHKEAGL 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	80/248 (32%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056	91/294 (31%)
		Tryp_SPc	312..551	CDD:238113	80/248 (32%)