DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tpr and f7i

DIOPT Version :9

Sequence 1:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_775335.1	Gene:	f7i / 282671	ZFINID:	ZDB-GENE-021206-10	Length:	443	Species:	Danio rerio

Alignment Length:	289	Identity:	91/289 - (31%)
Similarity:	135/289 - (46%)	Gaps:	49/289 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 RNCS------------DCV------CGIANIQK-----RIVGGQETEVHQYPWVAMLLYGGRFYC 152
            |:||            .||      ||...:||     :.:||........||..::.|.|...|
Zfish   147 RSCSCAEGYALADDGTSCVSQVDYPCGKIPVQKNTSQNQFLGGIHCPRGHCPWQVLIDYNGESVC 211

  Fly   153 AASLLNDQFLLTASHCVYGFRKERISVRLL--EHDRKMSHMQKIDRKVAEVITHPKYNARNYDND 215
            ..:||...:|:||:|||:  :|:...::.:  |||..:....:...:|:.|..||.|:....|:|
Zfish   212 GGALLEGPWLITAAHCVH--QKDTRFLKAVTGEHDLDVLDGSEEPYEVSAVFIHPNYDPETLDSD 274

  Fly   216 IAIIKLDEPVEFNEVLHPVCMPTP--GRS--FKGENGIVTGWGALKVG----------GPTSDTL 266
            :|:::|..||:.:....|:|:|||  .||  :......::|||....|          ||.|.||
Zfish   275 LALLRLRVPVQRSLYAVPICLPTPQLARSELWAARFHTLSGWGTRTAGHNLRREKGLKGPASGTL 339

  Fly   267 QEVQVPILSQDECRKSRYGN-KITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVS 330
            |.:.||:|...:|     || ..|.||.|.||.||...||:|..|.|| :...|.... :.||||
Zfish   340 QRLAVPLLPAAQC-----GNANTTANMFCAGYTEGDHASCRGHDGSPL-VTRYGETSF-LTGVVS 397

  Fly   331 WGEGCAKAGYPGVYARVNRYGTWIKNLTK 359
            ||.||...||..:|.:|..:..|:..:.|
Zfish   398 WGRGCGPPGYYWIYTKVENFLIWMDTVMK 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	80/244 (33%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	81/245 (33%)
f7i	NP_775335.1	GLA	20..82	CDD:214503
		EGF_CA	<91..120	CDD:238011
		FXa_inhibition	129..164	CDD:291342	3/16 (19%)
		Tryp_SPc	188..420	CDD:214473	80/240 (33%)
		Tryp_SPc	188..420	CDD:238113	80/240 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910