Protein Alignment tpr and Tmprss5

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_695223.2
• Gene: Tmprss5 / 266681
• RGDID: 628625
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 366
• Identity: 129/366 - (35%)
• Similarity: 179/366 - (48%)
• Gaps: 64/366 - (17%)

  Fly     5 WLCLLIC-----LALSCGPSQSASQDRATNQTA---ASPLLKQSQNTFIQWVLSLLPQRPGSSDS 61
            |  ||:|     .||.....||....|.|...|   :...|.:||. |.|     |..||||
  Rat   121 W--LLVCHEGWNPALGMHICQSLGYFRLTQHKAVNLSDIKLNRSQE-FAQ-----LSARPGS--- 174

  Fly    62 ENATLATLSSSSMMPDAASTTSTTTPAPSSSTTTTRRATTPAPPTLNPPRNCSDCVCGIANIQKR 126
                   |...:..|        :|..||....:.:               ||:  ||...:..|
  Rat   175 -------LVEEAWQP--------STNCPSGRIVSLK---------------CSE--CGARPLASR 207

  Fly   127 IVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERIS-----VRLLEHDR 186
            |||||.....::||.|.::.|.|..|.||:|...:::||:||:|.||..|:|     ..|:.|..
  Rat   208 IVGGQAVASGRWPWQASVMLGSRHTCGASVLAPYWVVTAAHCMYSFRLSRLSSWRVHAGLVSHSA 272

  Fly   187 KMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSF-KGENGIV 250
            ...|...:   |.::|.||.|:|:|:|.|:|:::|..|:.|::.:..||:|...:.| :|....|
  Rat   273 VRQHQGTM---VEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVSAVCLPAKEQHFPQGSQCWV 334

  Fly   251 TGWGALKVGGP-TSDTLQEVQVPILSQDECRKS-RYGNKITDNMLCGGYDEGGKDSCQGDSGGPL 313
            :|||....... :|||||:..||:||.|.|..| .|...:|..|||.||.:|..|:|||||||||
  Rat   335 SGWGHTDPSHTHSSDTLQDTMVPLLSTDLCNSSCMYSGALTHRMLCAGYLDGRADACQGDSGGPL 399

  Fly   314 HIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI 354
             :..||...| :.||||||.|||:...|||||:|..:..||
  Rat   400 -VCPSGDTWH-LVGVVSWGRGCAEPNRPGVYAKVAEFLDWI 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	98/236 (42%)
Tmprss5	NP_695223.2	SRCR_2	106..203	CDD:464747	30/124 (24%)
		Tryp_SPc	208..441	CDD:238113	98/236 (42%)