Protein Alignment tpr and TPSG1

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_036599.4
• Gene: TPSG1 / 25823
• HGNCID: 14134
• Length: 321
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 92/263 - (34%)
• Similarity: 127/263 - (48%)
• Gaps: 30/263 - (11%)

  Fly   106 TLNPPRNCSDCVCG---IANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASH 167
            ||.|.       ||   :::...|||||.......:||.|.|.......|..|||:.|::|||:|
Human    21 TLQPG-------CGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAH 78

  Fly   168 CVYG-FRKERISVRLLEHDRKMS-HMQKIDRKVAEVITHPKYNAR-NYDNDIAIIKLDEPVEFNE 229
            |..| .......|.|.|.:..:| |..    .|.::|.|...:.: ....|||:::|..||..:.
Human    79 CFSGSLNSSDYQVHLGELEITLSPHFS----TVRQIILHSSPSGQPGTSGDIALVELSVPVTLSS 139

  Fly   230 VLHPVCMPTPGRSF-KGENGIVTGWGALKVGGPTSD--TLQEVQVPILSQDECRKSRY----GNK 287
            .:.|||:|.....| .|....|||||..:.|.|...  :|:||:|.::..:.||:. |    |:.
Human   140 RILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRD-YPGPGGSI 203

  Fly   288 ITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGT 352
            :..:|||.   .|..|:||.||||||....:|....  ||.|||||||.:...||||.||..|..
Human   204 LQPDMLCA---RGPGDACQDDSGGPLVCQVNGAWVQ--AGTVSWGEGCGRPNRPGVYTRVPAYVN 263

  Fly   353 WIK 355
            ||:
Human   264 WIR 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	86/239 (36%)
TPSG1	NP_036599.4	Tryp_SPc	38..268	CDD:238113	86/239 (36%)