Protein Alignment tpr and KLK5

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 87/244 - (35%)
• Similarity: 137/244 - (56%)
• Gaps: 26/244 - (10%)

  Fly   126 RIVGGQETEVHQYPW-VAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMS 189
            ||:.|.:.::|..|| .|:||...:.||.|.|::.|:||||:||    ||:...|||..:  .:|
Human    66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGHY--SLS 124

  Fly   190 HMQKIDRKV---AEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKGENGIVT 251
            .:.:..:::   .:.|.||.|:...:.||:.:|||:..:...:.:.|:.:.:...| .|...:|:
Human   125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS-AGTKCLVS 188

  Fly   252 GWGALK---VGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPL 313
            |||..|   |..|  ..||.:.:.:|||..| :..|..:|.|.|.|.| |:.|:||||||||||
Human   189 GWGTTKSPQVHFP--KVLQCLNISVLSQKRC-EDAYPRQIDDTMFCAG-DKAGRDSCQGDSGGP- 248

  Fly   314 HIVASGTREHQIAGVVSWGE-GCAKAGYPGVYARVNRYGTWIKNLTKQA 361
             :|.:|:    :.|:||||: .||:...||||..:.::..||:. |.||
Human   249 -VVCNGS----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE-TIQA 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	83/236 (35%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/1 (100%)
		Tryp_SPc	66..285	CDD:214473	82/235 (35%)