Protein Alignment tpr and Klkb1

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_036857.2
• Gene: Klkb1 / 25048
• RGDID: 67382
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 354
• Identity: 112/354 - (31%)
• Similarity: 155/354 - (43%)
• Gaps: 84/354 - (23%)

  Fly    43 TFIQ-----------------WVLSLLPQRPGSSDSENATLATLSSSSMMPDAASTTSTTTPAPS 90
            ||:|                 :..|||||   ...:|....:...|:.     .|.|..|..|..
  Rat   310 TFVQGADACQETCTKTIRCQFFTYSLLPQ---DCKAEGCKCSLRLSTD-----GSPTRITYEAQG 366

  Fly    91 SSTTTTRRATTPAPPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAML---LYGGRFYC 152
            ||..:.|         |......|||.   ..|..|||||..:.:.::||...|   |......|
  Rat   367 SSGYSLR---------LCKVVESSDCT---TKINARIVGGTNSSLGEWPWQVSLQVKLVSQNHMC 419

  Fly   153 AASLLNDQFLLTASHC-----------VYGFRKERISVRLLEHDRKMSHMQKIDRK-----VAEV 201
            ..|::..|::|||:||           :||               .:.::.:|..|     :.|:
  Rat   420 GGSIIGRQWILTAAHCFDGIPYPDVWRIYG---------------GILNLSEITNKTPFSSIKEL 469

  Fly   202 ITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKGE------NGIVTGWGALKVGG 260
            |.|.||.......|||:|||..|:.:.|...|:|:|:     |.:      |..|||||..|..|
  Rat   470 IIHQKYKMSEGSYDIALIKLQTPLNYTEFQKPICLPS-----KADTNTIYTNCWVTGWGYTKERG 529

  Fly   261 PTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQI 325
            .|.:.||:..:|::..:||:|......||..|:|.||.|||.|:|:|||||||....||  ..|:
  Rat   530 ETQNILQKATIPLVPNEECQKKYRDYVITKQMICAGYKEGGIDACKGDSGGPLVCKHSG--RWQL 592

  Fly   326 AGVVSWGEGCAKAGYPGVYARVNRYGTWI 354
            .|:.|||||||:...||||.:|..|..||
  Rat   593 VGITSWGEGCARKEQPGVYTKVAEYIDWI 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	89/253 (35%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519	17/81 (21%)
		Tryp_SPc	391..621	CDD:238113	87/251 (35%)