DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tpr and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	305	Identity:	95/305 - (31%)
Similarity:	145/305 - (47%)	Gaps:	36/305 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 ATLATLSSSSMMPDAASTTSTT-TPAPSSSTTTTRRATTPAPPTLNPPRNCSDCVCGIANIQKRI 127
            :.|..||||..:..|.|...|: |...:.:..|......|...||:               ::||
Mouse   137 SVLRRLSSSGNLEIAPSNEITSLTDQDTENVLTQECGARPDLITLS---------------EERI 186

  Fly   128 VGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKER-------ISVRLLEHD 185
            :||.:.|...:||...|......:|..:|:::.::|||:||...:...:       :|.
Mouse   187 IGGMQAEPGDWPWQVSLQLNNVHHCGGALISNMWVLTAAHCFKSYPNPQYWTATFGVST------ 245

  Fly   186 RKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRS-FKGENGI 249
              ||...::  :|..::.|..|::...|||||:::||..|.|:..:|.||:|...:: ..|....
Mouse   246 --MSPRLRV--RVRAILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAATQNIIPGSVAY 306

  Fly   250 VTGWGALKVGGPTSDTLQEVQVPILSQDECR-KSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPL 313
            |||||:|..||.....|::.:|.|:|.:||. .:.|...:...|||.|...|..|:|||||||||
Mouse   307 VTGWGSLTYGGNAVTNLRQGEVRIISSEECNTPAGYSGSVLPGMLCAGMRSGAVDACQGDSGGPL 371

  Fly   314 HIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLT 358
             :.....|...:.|:||||..|.....||||.||..|..||:..|
Mouse   372 -VQEDSRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWIRQQT 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	79/236 (33%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	80/237 (34%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699	0/2 (0%)
		Tryp_SPc	185..411	CDD:214473	79/236 (33%)
		Tryp_SPc	186..414	CDD:238113	80/238 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3995
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960