Protein Alignment tpr and Habp2

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001316864.1
• Gene: Habp2 / 226243
• MGIID: 1196378
• Length: 554
• Species: Mus musculus
• Alignment Length: 285
• Identity: 90/285 - (31%)
• Similarity: 143/285 - (50%)
• Gaps: 41/285 - (14%)

  Fly   102 PAPPTLNPPRNCSDCV--------CGIANIQ----KRIVGGQETEVHQYPWVAML---------L 145
            |.|.|.||..:..:.|        ||...:.    |||.||.::...::||...|         :
Mouse   271 PVPDTPNPVESLLEPVMELPGFESCGKTEVAEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSM 335

  Fly   146 YGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNAR 210
            ..|.| |..:|::..::|||:||. ....:.:.|.|.:.|.|.:...:...:|.:::.:.:||.|
Mouse   336 PQGHF-CGGALIHPCWVLTAAHCT-DINTKHLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNER 398

  Fly   211 NY--DNDIAIIKLDEPVEFNEVLH-----PVCMPT-PGRSFKGENGIVTGWGALKVGGPTSDTLQ 267
            :.  .||||::|| :||..:..|.     .||:|: |..|  |....::|||..:. |..|..|.
Mouse   399 DEIPHNDIALLKL-KPVGGHCALESRYVKTVCLPSDPFPS--GTECHISGWGVTET-GEGSRQLL 459

  Fly   268 EVQVPILSQDECR-KSRYGNKITDNMLC-GGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVS 330
            :.:|.:::...|. :..|.:.|.|:|:| |...:.|.|:|||||||||.....||  :.:.|:||
Mouse   460 DAKVKLIANPLCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGT--YYVYGIVS 522

  Fly   331 WGEGCAKAGYPGVYARVNRYGTWIK 355
            ||:.|.|.  ||||.:|.::..|||
Mouse   523 WGQECGKK--PGVYTQVTKFLNWIK 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	80/248 (32%)
Habp2	NP_001316864.1	EGF_CA	67..103	CDD:238011
		EGF_CA	150..182	CDD:238011
		KR	187..271	CDD:238056	90/285 (32%)
		Tryp_SPc	308..547	CDD:238113	80/248 (32%)