Protein Alignment tpr and Tmprss4

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_663378.1
• Gene: Tmprss4 / 214523
• MGIID: 2384877
• Length: 435
• Species: Mus musculus
• Alignment Length: 372
• Identity: 108/372 - (29%)
• Similarity: 161/372 - (43%)
• Gaps: 99/372 - (26%)

  Fly    53 PQRPGSS---DSENATLATLSSSSMMPDAASTTSTTTPAPSSSTTTTRRA-------TTPA---- 103
            |::||.:   ..:.:||..|       |||:.|..:....:.:....:.|       :.||
Mouse    95 PEKPGVAVRLSKDRSTLQVL-------DAATGTWASVCFDNFTEALAKTACRQMGYDSQPAFRAV 152

  Fly   104 --PPTLNPP-----------------RNCSD-------CV-CGIANIQKRIVGGQETEVHQYPWV 141
              .|..|.|                 |:|..       |: ||.:....|:|||.|..|..:||.
Mouse   153 EIRPDQNLPVAQVTGNSQELQVQNGSRSCLSGSLVSLRCLDCGKSLKTPRVVGGVEAPVDSWPWQ 217

  Fly   142 AMLLYGGRFYCAASLLNDQFLLTASHCVYGFR--------KERISVRLLEHDRKMSHMQKIDRKV 198
            ..:.|..:..|..|:|:..::|||:||   ||        |.|....:|.:...:        .|
Mouse   218 VSIQYNKQHVCGGSILDPHWILTAAHC---FRKYLDVSSWKVRAGSNILGNSPSL--------PV 271

  Fly   199 AEVI------THPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKGENGI------VT 251
            |::.      .:||      :.|||::||..|:.|:..:.|:|:|     |..|..:      |.
Mouse   272 AKIFIAEPNPLYPK------EKDIALVKLQMPLTFSGSVRPICLP-----FSDEVLVPATPVWVI 325

  Fly   252 GWGALKV-GGPTSDTLQEVQVPILSQDECR-KSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPL- 313
            |||..:. ||..||.|.:..|.::....|. :..|..::|..|||.|..:||||:|||||||||
Mouse   326 GWGFTEENGGKMSDMLLQASVQVIDSTRCNAEDAYEGEVTAEMLCAGTPQGGKDTCQGDSGGPLM 390

  Fly   314 -HIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLTK 359
             |     :.:.|:.|:||||.||.....||||.:|..|..||.|:.|
Mouse   391 YH-----SDKWQVVGIVSWGHGCGGPSTPGVYTKVTAYLNWIYNVRK 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	84/252 (33%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:470597	16/95 (17%)
		Tryp_SPc	202..427	CDD:214473	83/251 (33%)