Protein Alignment tpr and PRSS55

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_047277448.1
• Gene: PRSS55 / 203074
• HGNCID: 30824
• Length: 376
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 100/307 - (32%)
• Similarity: 152/307 - (49%)
• Gaps: 29/307 - (9%)

  Fly    70 SSSSMMPDAASTTSTTTPAPSSSTTTTRRATTPA-----PPTLNPPRNCSDCVCGIANI------ 123
            |.|.::.......||..|||.|...::....|..     |.:..||.      ||..:|
Human    30 SLSELLSRMGMRISTWKPAPPSPVPSSHWMLTKCFPFSFPLSFFPPE------CGDRSIFEGRTR 88

  Fly   124 QKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYG--FRKERISVRLLEHDR 186
            ..||.||.|.||.::||...:......:|..|:||..::|||:||:|.  ...|.:||.|..:|.
Human    89 YSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDL 153

  Fly   187 KMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPT-PGRSFKGENGIV 250
            ....|:  .::||.:|.|..:...|.|||||::.|..|::.:::..|:|:|| ||.:...|.. |
Human   154 TSPSME--IKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECW-V 215

  Fly   251 TGWGALKVGGPTS--DTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPL 313
            .|||........|  ..|.:..:.|:..:||  |:...|:|.||||.||.....|:|:|||||||
Human   216 AGWGQTNAADKNSVKTDLMKAPMVIMDWEEC--SKMFPKLTKNMLCAGYKNESYDACKGDSGGPL 278

  Fly   314 HIVAS-GTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLTK 359
            ..... |.:.:|: |::|||:.|.:...||:|..:..|..||:.:|:
Human   279 VCTPEPGEKWYQV-GIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQ 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	83/234 (35%)
PRSS55	XP_047277448.1	Tryp_SPc	92..322	CDD:238113	83/235 (35%)