DRSC/TRiP Functional Genomics Resources

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Protein Alignment tpr and Tmprss15

DIOPT Version :9

Sequence 1:NP_611611.1 Gene:tpr / 37486 FlyBaseID:FBgn0034661 Length:372 Species:Drosophila melanogaster
Sequence 2:NP_032967.1 Gene:Tmprss15 / 19146 MGIID:1197523 Length:1069 Species:Mus musculus


Alignment Length:369 Identity:114/369 - (30%)
Similarity:177/369 - (47%) Gaps:54/369 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 SQSASQDRATNQTAASPLLKQSQNTFIQ------WVLSLLPQRPGSSDSENATLATL-SSSSMMP 76
            |..||..|..|.|       :|.|..:|      |.::..........:|...|..| |::|.||
Mouse   717 SDEASCVRFLNGT-------RSNNGLVQFNIHSIWHIACAENWTTQISNEVCHLLGLGSANSSMP 774

  Fly    77 DAASTTS-----TTTPAPSSSTTTTRRATTPAPPTLNPPRN------CSDCVCG----IANIQKR 126
              .|:|.     ....||:.|...|        |:|...::      |:...||    ...:..:
Mouse   775 --ISSTGGGPFVRVNQAPNGSLILT--------PSLQCSQDSLILLQCNHKSCGEKKVTQKVSPK 829

  Fly   127 IVGGQETEVHQYPWVAMLLY----GGRFYCAASLLNDQFLLTASHCVYGFRKERISVRL-----L 182
            ||||.:.:...:|||..|.:    ..|..|.|||::..:|::|:||||  |:.....|.     |
Mouse   830 IVGGSDAQAGAWPWVVALYHRDRSTDRLLCGASLVSSDWLVSAAHCVY--RRNLDPTRWTAVLGL 892

  Fly   183 EHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSF-KGE 246
            .....::..|.:.|.|.:::.:|.|:.|...||||::.|:..|.:.:.:.|:|:|...:.| .|.
Mouse   893 HMQSNLTSPQVVRRVVDQIVINPHYDRRRKVNDIAMMHLEFKVNYTDYIQPICLPEENQIFIPGR 957

  Fly   247 NGIVTGWGALKV-GGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSG 310
            ...:.|||..|: .|.|.|.|:|..||::|.::|::......||::|:|.||:|||.||||||||
Mouse   958 TCSIAGWGYDKINAGSTVDVLKEADVPLISNEKCQQQLPEYNITESMICAGYEEGGIDSCQGDSG 1022

  Fly   311 GPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI 354
            |||  :........:.||.|:|..||...:||||.||:::..||
Mouse  1023 GPL--MCQENNRWFLVGVTSFGVQCALPNHPGVYVRVSQFIEWI 1064

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tprNP_611611.1 Tryp_SPc 126..354 CDD:214473 84/238 (35%)
Tryp_SPc 127..356 CDD:238113 86/239 (36%)
Tmprss15NP_032967.1 SEA 53..154 CDD:214554
LDLa 228..261 CDD:197566
CUB 270..376 CDD:294042
MAM 392..549 CDD:279023
MAM 392..547 CDD:99706
CUB 569..676 CDD:278839
LDLa 688..722 CDD:238060 2/4 (50%)
SR 723..816 CDD:214555 23/109 (21%)
SRCR 728..819 CDD:278931 22/107 (21%)
Tryp_SPc 829..1064 CDD:214473 84/238 (35%)
Tryp_SPc 830..1066 CDD:238113 86/239 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm11120
orthoMCL 1 0.900 - - OOG6_100031
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R8078
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.840

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