DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tpr and svh-1

DIOPT Version :9

Sequence 1:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	272	Identity:	90/272 - (33%)
Similarity:	141/272 - (51%)	Gaps:	57/272 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 CGIANIQ-----------KRIVGGQETEVHQYPWVAMLLYGG--RFYCAASLLNDQFLLTASHCV 169
            ||:..::           .|:|||.||....:||.|.|....  ..:|.||:|:...|:||:||
Worm   693 CGLRYVEVNARDAAKSRIARVVGGFETVPGAFPWTAALRNKATKAHHCGASILDKTHLITAAHC- 756

  Fly   170 YGFRK-ERISV----------RLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDE 223
              |.: ||:|.          ...:.:.::.::|:|.       .:|.|. ..:.:||||:::..
Worm   757 --FEEDERVSSYEVVVGDWDNNQTDGNEQIFYLQRIH-------FYPLYK-DIFSHDIAILEIPY 811

  Fly   224 P-VEFNEVLHPVCMP------TPGRSFKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDEC-R 280
            | :||||...|:|:|      ||||..     :|:|||::  |...::.||...:||:::.:| .
Worm   812 PGIEFNEYAQPICLPSKDFVYTPGRQC-----VVSGWGSM--GLRYAERLQAALIPIINRFDCVN 869

  Fly   281 KSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTRE---HQIAGVVSWGEGCAKAGYPG 342
            .|:..:.::.:..|.||.|||.||||||||||.    :..||   ..:|||:|||:|||:...||
Worm   870 SSQIYSSMSRSAFCAGYLEGGIDSCQGDSGGPF----ACRREDGAFVLAGVISWGDGCAQKKQPG 930

  Fly   343 VYARVNRYGTWI 354
            :|..|..|.:||
Worm   931 IYTMVAPYLSWI 942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	86/251 (34%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	87/252 (35%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	87/252 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910