Protein Alignment tpr and CFD

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 78/256 - (30%)
• Similarity: 117/256 - (45%)
• Gaps: 32/256 - (12%)

  Fly   109 PPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFR 173
            |||.             ||:||:|.|.|..|::|.:...|...|...|:.:|::|:|:||:....
Human    28 PPRG-------------RILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAA 79

  Fly   174 KERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPT 238
            ..::.|.|..|........|....|...:.||.......|:|:.:::|.|    ...|.|...|.
Human    80 DGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSE----KATLGPAVRPL 140

  Fly   239 PGRSF-----KGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDEC-RKSRYGNKITDNMLCGGY 297
            |.:..     .|....|.|||.:...|...|:||.|.:|:|.:..| |::.:...||:.::|.
Human   141 PWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA-- 203

  Fly   298 DEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEG-CAKAGYPGVYARVNRYGTWIKNL 357
            :...:|||:|||||||  |..|..|    |||:.|.. |.....||:|.||..|..||.::
Human   204 ESNRRDSCKGDSGGPL--VCGGVLE----GVVTSGSRVCGNRKKPGIYTRVASYAAWIDSV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	74/235 (31%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	74/236 (31%)