Protein Alignment tpr and Klk1b1

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_034775.1
• Gene: Klk1b1 / 16623
• MGIID: 892019
• Length: 261
• Species: Mus musculus
• Alignment Length: 252
• Identity: 85/252 - (33%)
• Similarity: 134/252 - (53%)
• Gaps: 27/252 - (10%)

  Fly   123 IQKRIVGGQETEVHQYPW-VAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDR 186
            :|.|||||.:.|.:..|| ||:..| ..:.|...||:..::|||:||.|    |:.:|.|.:::.
Mouse    21 VQSRIVGGFKCEKNSQPWHVAVYRY-KEYICGGVLLDANWVLTAAHCYY----EKNNVWLGKNNL 80

  Fly   187 KMSHMQKIDRKVAEVITHPKYNA---RN--------YDNDIAIIKLDEPVEFNEVLHPVCMPTPG 240
            .........|.|::...||.||.   ||        |..|:.:::|.:|.:..:|:.|:.:||..
Mouse    81 YQDEPSAQHRLVSKSFLHPCYNMSLHRNRIQNPQDDYSYDLMLLRLSKPADITDVVKPIALPTEE 145

  Fly   241 RSFKGENGIVTGWGA-LKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDS 304
            ... |...:.:|||: :.|....:..||.|.:.:|..::|.|: |..|:||.|||.|...||||:
Mouse   146 PKL-GSTCLASGWGSIIPVKFQYAKDLQCVNLKLLPNEDCDKA-YVQKVTDVMLCAGVKGGGKDT 208

  Fly   305 CQGDSGGPLHIVASGTREHQIAGVVSWG-EGCAKAGYPGVYARVNRYGTWIKNLTKQ 360
            |:|||||||  :..|.    :.|:.||| ..|.:...||||.::.::.:|||:...|
Mouse   209 CKGDSGGPL--ICDGV----LQGLTSWGYNPCGEPKKPGVYTKLIKFTSWIKDTLAQ 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	81/242 (33%)
Klk1b1	NP_034775.1	Tryp_SPc	24..253	CDD:214473	80/241 (33%)