Protein Alignment tpr and Klk1b21

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_011249110.1
• Gene: Klk1b21 / 16616
• MGIID: 892022
• Length: 296
• Species: Mus musculus
• Alignment Length: 285
• Identity: 86/285 - (30%)
• Similarity: 132/285 - (46%)
• Gaps: 66/285 - (23%)

  Fly   123 IQKRIVGGQETEVHQYPW-VAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISV-----RL 181
            :|.|||||...|.:..|| ||:..| .::.|...|||..::|||:|| ||....:.:|     :|
Mouse    21 VQSRIVGGFNCEKNSQPWHVAVFRY-NKYICGGVLLNPNWVLTAAHC-YGNATSQYNVWLGKNKL 83

  Fly   182 LEHDRKMSHMQKIDRKVAEVITHPKYNAR-----------NYDNDIAIIKLDEPVEFNEVLHPVC 235
            .:|:....|     |.|::...||.||..           :|.||:.:::|.:|.:..:.:.|:.
Mouse    84 FQHESSAQH-----RLVSKSFPHPDYNMSLMNDHTPHPEDDYSNDLMLLRLSKPADITDAVKPID 143

  Fly   236 MPTPGRSFKGENGIVTGWGALKV--------------GGPTSDTLQEVQVPI------------- 273
            :||..... |...:.:|||::..              ||.....|..|..|:
Mouse   144 LPTEEPKL-GSTCLASGWGSITPTKCESAPRNIARCRGGAEGPGLGPVHHPLSLSSTGQIPNDLQ 207

  Fly   274 ------LSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWG 332
                  |..:.|.|: |.:|:||.|||.|...||||:|.|||||||  :..|.    :.|:.|||
Mouse   208 CGFIKPLPNENCAKA-YIHKVTDVMLCAGEMGGGKDTCAGDSGGPL--ICDGV----LQGITSWG 265

  Fly   333 E-GCAKAGYPGVYARVNRYGTWIKN 356
            . .|||...|.:|.::.::.:|||:
Mouse   266 SIPCAKPNAPAIYTKLIKFTSWIKD 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	83/279 (30%)
Klk1b21	XP_011249110.1	Tryp_SPc	25..291	CDD:238113	84/281 (30%)