Protein Alignment tpr and Tmprss2

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_008766769.1
• Gene: Tmprss2 / 156435
• RGDID: 620766
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 312
• Identity: 105/312 - (33%)
• Similarity: 150/312 - (48%)
• Gaps: 52/312 - (16%)

  Fly    71 SSSMMPDAASTTSTTTPAPSSSTTTTRRATTPAPPTLNPPRNCSD-------CV-CGIANI--QK 125
            ||..:||.:..||......|:......:       .|....:||.       |: ||:.::  |.
  Rat   195 SSQGIPDQSGATSFMKLNVSAGNVDLYK-------KLYHSDSCSSRMVVSLRCIECGVRSVRRQS 252

  Fly   126 RIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCV-------------YGFRKERI 177
            |||||.......:||...|...|...|..|::..::::||:|||             .|..|:.:
  Rat   253 RIVGGSTASPGDWPWQVSLHVQGIHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILKQSL 317

  Fly   178 SVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRS 242
            ......|            :|.:||:||.|:::..:||||::||..|:.||:|:.|||:|.||..
  Rat   318 MFYGSRH------------QVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDVVKPVCLPNPGMM 370

  Fly   243 FK-GENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECR-KSRYGNKITDNMLCGGYDEGGKDSC 305
            .. .:...::||||....|.|||.|....||::...:|. |..|.|.||..|:|.|:.:|..|||
  Rat   371 LDLAQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSC 435

  Fly   306 QGDSGGPLHIVASGTREHQI---AGVVSWGEGCAKAGYPGVYARVNRYGTWI 354
            ||||||||     .|.:::|   .|..|||.|||||..||||..|..:..||
  Rat   436 QGDSGGPL-----VTLKNEIWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWI 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	90/246 (37%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:464747	13/58 (22%)
		Tryp_SPc	254..485	CDD:238113	90/246 (37%)