Protein Alignment tpr and Hpn

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001263198.1
• Gene: Hpn / 15451
• MGIID: 1196620
• Length: 445
• Species: Mus musculus
• Alignment Length: 265
• Identity: 98/265 - (36%)
• Similarity: 131/265 - (49%)
• Gaps: 37/265 - (13%)

  Fly   113 CSDCVCGIANIQ-KRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKER 176
            |.|  ||...:. .||||||::.:.::||...|.|.|...|..|||:..::|||:||
Mouse   178 CQD--CGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHC-------- 232

  Fly   177 ISVRLLEHDRKMSHMQKIDRKVAE------------VITHPKY------NARNYDNDIAIIKLDE 223
                ..|.:|.:|..:.....||.            ||.|..|      ......||||::.|..
Mouse   233 ----FPERNRVLSRWRVFAGAVARTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSS 293

  Fly   224 PVEFNEVLHPVCMPTPGRSF-KGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRK-SRYGN 286
            .:...|.:.|||:|..|::. .|:...|||||..:..|..:..|||.:|||:|.:.|.. ..|||
Mouse   294 SLPLTEYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQAMVLQEARVPIISNEVCNSPDFYGN 358

  Fly   287 KITDNMLCGGYDEGGKDSCQGDSGGPL--HIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNR 349
            :|...|.|.||.|||.|:||||||||.  ....|||...::.|:||||.|||.|..||||.:|..
Mouse   359 QIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISGTSRWRLCGIVSWGTGCALARKPGVYTKVTD 423

  Fly   350 YGTWI 354
            :..||
Mouse   424 FREWI 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	93/250 (37%)
Hpn	NP_001263198.1	Hepsin-SRCR	79..187	CDD:462736	4/10 (40%)
		Tryp_SPc	191..428	CDD:238113	91/248 (37%)