Protein Alignment tpr and F7

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_034302.2
• Gene: F7 / 14068
• MGIID: 109325
• Length: 446
• Species: Mus musculus
• Alignment Length: 288
• Identity: 106/288 - (36%)
• Similarity: 149/288 - (51%)
• Gaps: 36/288 - (12%)

  Fly    95 TTRRATTPAPPTLNPPR-NCSDCV---CG-IANIQK--------RIVGGQETEVHQYPWVAMLLY 146
            |.|..:.....||.|.. :|...|   || |..::|        |||||......:.||.|:|..
Mouse   149 TKRTCSCHEDYTLQPDEVSCKPKVEYPCGRIPVVEKRNSSSRQGRIVGGNVCPKGECPWQAVLKI 213

  Fly   147 GGRFYCAASLLNDQFLLTASHCVYGFRK-ERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNAR 210
            .|...|.|.||:.::::||:||....|. ..|:|.:.|||.......:..|:|.:||...||...
Mouse   214 NGLLLCGAVLLDARWIVTAAHCFDNIRYWGNITVVMGEHDFSEKDGDEQVRRVTQVIMPDKYIRG 278

  Fly   211 NYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKGENGI-------VTGWGALKVGGPTSDTLQE 268
            ..::|||:::|..||.|.:.:.|:|:|.  :|| .||.:       |:|||.|...|.|:..|..
Mouse   279 KINHDIALLRLHRPVTFTDYVVPLCLPE--KSF-SENTLARIRFSRVSGWGQLLDRGATALELMS 340

  Fly   269 VQVPILSQDEC----RKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREH---QIA 326
            ::||.|...:|    :.|....|||:||.|.||.:|.||:|:||||||     ..|..|   .:.
Mouse   341 IEVPRLMTQDCLEHAKHSSNTPKITENMFCAGYMDGTKDACKGDSGGP-----HATHYHGTWYLT 400

  Fly   327 GVVSWGEGCAKAGYPGVYARVNRYGTWI 354
            ||||||||||..|:.|||.||::|..|:
Mouse   401 GVVSWGEGCAAIGHIGVYTRVSQYIDWL 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	94/243 (39%)
F7	NP_034302.2	GLA	24..85	CDD:214503
		EGF_CA	87..123	CDD:238011
		FXa_inhibition	132..168	CDD:464251	5/18 (28%)
		Tryp_SPc	194..431	CDD:238113	94/243 (39%)