Protein Alignment tpr and F10

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001229297.1
• Gene: F10 / 14058
• MGIID: 103107
• Length: 493
• Species: Mus musculus
• Alignment Length: 338
• Identity: 102/338 - (30%)
• Similarity: 164/338 - (48%)
• Gaps: 53/338 - (15%)

  Fly    60 DSENATLATLSSSSMMPDAASTTSTTTPAPSSSTTTTRRATTPA--------------------P 104
            :.:|:.:.:.:|...:.:...:..:|.|.|....||.||..:.|                    .
Mouse   154 EEQNSVVCSCASGYFLGNDGKSCISTAPFPCGKITTGRRKRSVALNTSDSELDLEDALLDEDFLS 218

  Fly   105 PTLNP----------PRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLL-YGGRFYCAASLLN 158
            ||.||          |...||.:.       |||||:|.:..:.||.|:|: .....:|..::||
Mouse   219 PTENPIELLNLNETQPERSSDDLV-------RIVGGRECKDGECPWQALLINEDNEGFCGGTILN 276

  Fly   159 DQFLLTASHCVYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDE 223
            :.::|||:||::..|  |..||:.:.:.:.....::..:|..||.|.|:....||.|||:::|..
Mouse   277 EFYILTAAHCLHQAR--RFKVRVGDRNTEKEEGNEMVHEVDVVIKHNKFQRDTYDYDIAVLRLKT 339

  Fly   224 PVEFNEVLHPVCMP----TPGRSFKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRY 284
            |:.|...:.|.|:|    ........:.|||:|:|.....|..|:.|:.::||.:.::.|:.|.
Mouse   340 PITFRMNVAPACLPQKDWAESTLMTQKTGIVSGFGRTHEKGRQSNILKMLEVPYVDRNTCKLST- 403

  Fly   285 GNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTR---EHQIAGVVSWGEGCAKAGYPGVYAR 346
            ...||.||.|.||:...:|:|||||||| |:    ||   .:.:.|:||||||||:.|..|:|.:
Mouse   404 SFSITQNMFCAGYEAKLEDACQGDSGGP-HV----TRFKNTYYVTGIVSWGEGCARKGKYGIYTK 463

  Fly   347 VNRYGTWIKNLTK 359
            |..:..||....|
Mouse   464 VTTFLKWIDRSMK 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	83/236 (35%)
F10	NP_001229297.1	GLA	36..97	CDD:214503
		EGF_CA	98..134	CDD:238011
		FXa_inhibition	141..176	CDD:464251	2/21 (10%)
		Tryp_SPc	244..473	CDD:238113	83/236 (35%)